despite a lot of research, the etiology and progression of breast cancer remain incompletely understood. recently, human cytomegalovirus (hcmv) was reported as a risk factor for breast cancer. the aim of this study was to know whether breast cancer could be caused by cytomegalovirus or not? in this experiment seventeen samples of razi/a mice with spontaneous breast cancer were being gathered fr...

results of all participants, 104 patients (52%) were diagnosed with cmv infection. there was no significant difference between the two groups, with and without cmv infection, in terms of patient’s characteristics. the cmv infection, in patients receiving a transplanted organ from deceased donor, was significantly more prevalent than in those receiving kidney transplant from living donor (63% vs...

the polymerase chain reaction (pcr) as applied to detection of a foreign dna in clinical specimens could provide a sensitive instrument for rapid detection of viral dna persisting in tissues of patients suspected of latent infection. human cytomegalovirus (hcmv) dna was found in arterial plaques of patients with atherosclerotic lesions using a pcr assay with nested primer oligonucleotides deriv...

conclusions according to the low prevalence of hcmv in oscc, it seems that this virus plays a minor role in this kind of cancer at least in southeast of iran. more comprehensive studies are needed to investigate the oncomodulatory effect of this virus on oscc. results the mean age of the patients (66.7% female and 33.3% male) was 58.6 years. only three cases (6.3%) of the grade i, oscc biopsies...

patients and methods in this study, 87 specimens from iranian patients were amplified using nested pcr amplification of the ul97 gene. sequence analyses of products were performed for identifying the mutated codons. results the present study show that the most frequent gcv-resistant mutations occurred in codons a594v (26.43%), h520q (18.39%), and m460v (13.79%), consequently occurring at a low ...

human cytomegalovirus (hcmv, cmv) is a major infectious complication of renal transplantation. the objective of this survey was to optimize and establish a polymerase chain reaction (pcr) technique for rapid and early detection of cmv disease in renal transplant recipients. in a cross sectional study, a total of eighty-one edta-blood samples were collected as simple nonrandomized (sequential) w...

conclusions according to the results of this study, quantification of hcmv and ebv observed in this study is high in periodontal tissue samples of severe chronic periodontitis. background although studies focused mainly on the identification of periopathogenic bacteria, recent reports have suggested that various herpes viruses may also be involved in the occurrence and progression of different ...

objective(s):human cytomegalovirus (hcmv) remains a major morbidity and mortality cause in immuno suppressed patients. therefore, significant effort has been made towards the development of a vaccine. in this study, the expression of the pp65 and gb fusion peptides and fc domain of mouse igg2a as a novel delivery system for selective uptake of antigens by antigen-presenting cells (apcs) in pich...

A clinical study of lyophilized intravenous human immunoglobulin containing high-titer cytomegalovirus-neutralizing antibody for the treatment cytomegalovirus viremia after allogeneic hematopoietic stem cell transplantation